Perturbed length-dependent activation in human hypertrophic cardiomyopathy with sarcomere mutations in myosin and thin filament proteins

Sequeira V, Wijnker PJM, Nijenkamp LAM,  Najafi A, Witjas-Paalberends R, Regan JA, Boontje, N, ten Cate FJ, Carrier L, Sadayappan S, van Slegtenhorst MA, Zaremba R, Foster DB, Murphy AM, Poggesi C, dos Remedios C, Stienen GJM, Michels M, van der Velden J. Perturbed length-dependent activation in human hypertrophic cardiomyopathy with sarcomere mutations in myosin and thin filament proteins Circ Res. 2013 May 24;112(11):1491-505. doi: 10.1161/CIRCRESAHA.111.300436. Epub 2013 Mar 18F1000Editorial appears in Huke S and Knollman BJ, Is the Frank Starling Law Kaput? Circ. Res. May 24, 112(11):1409-1411 Faculty of 1000-Recommended: MacLeod, K. http://f1000.com/prime/718027223