Two fully funded postdoctoral research positions are available!

The Foster Lab is seeking highly motivated and enthusiastic postdoctoral fellows to contribute to their ongoing multi-omic, cell biological and in vivo analyses of the role of cardiac ATRA insufficiency in diastolic dysfunction and heart failure progression.

Come join this highly collaborative and interdisciplinary group.

Our laboratory utilizes diverse experimental techniques including targeted and shotgun proteomics, RNA-Seq, bioinformatics and data integration, to analyze both cellular and in vivo mouse models of diastolic dysfunction and heart failure. The Foster lab has longstanding collaborations with pre-eminent cardiobiologists in the Division of Cardiology and the Department of Pediatric Cardiology.

Post-doctoral fellows in the Foster Lab receive extensive mentoring by the PI, are encouraged to initiate projects and collaborations, regularly get involved in reviewing and grant writing as well as supervising interns. Fellows are also encouraged to learn new techniques, carry out collaborative research and attend national and international conferences.

Please contact Dr. D. Brian Foster with questions or an application via e-mail dbrianfoster@jhmi.edu with a CV and names of three references.

Postdoctoral position #1 Regulation of Protein and Gene Networks in Heart Failure by Retinoic Acid. The goal of the project is Identify the enzymes that metabolize Vitamin A to retinoic acid in the heart and manipulate them to boost cardiac retinoic acid and stimulate ATRA-dependent cardioprotective gene regulation.

Post-doctoral position #2.

Impact of cardiac ATRA insufficiency on heart function. Approaches span whole heart physiology to myocyte EC coupling to myofibril mechanics and biochemistry.

Requirements:

1. PhD with at least one first author publication in peer-reviewed journal(s).
2. For position #1: Expertise in molecular biology is required. Experience in NGS techniques, proteomics, bioinformatics, or immunofluorescence microscopy would be a plus.
3. For position #2: Experience with murine animal models is required. Experience in cardiac physiology (e.g., echo, ion-optix measurements of force & calcium are a plus.
4. Ability to work independently and as part of a team, excellent work ethic and being well organized