We are thrilled to announce that our collaboration with our colleague, developmental cardiobiologist, Dr. Chulan Kwon, has been selected for funding from the U.S. Department of Defense. The project explores understudied sequelae of Down Syndrome gene dosage leading to septal defects that cannot be inferred from genomic or transcriptomic data alone. We use the tools of proteomics to probe differences in post-translational modification, altered splicing, novel microproteins, and protein interactors of specific ion channels in the dorsal mesenchymal protrusion derived from the second heart field.
D. Brian Foster Ph.D.
Assistant Professor of Medicine
Division of Cardiology
Director, Laboratory of Cardiovascular Biochemistry
The Johns Hopkins University School of Medicine
Ross Research Building, Room 847
720 Rutland Avenue
Baltimore, MD 21205
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