Mitochondrial Protein Phosphorylation as a Regulatory Modality: Implications for Mitochondrial Dysfunction in Heart Failure

O’Rourke B, Van Eyk, JE and Foster DB, Mitochondrial Protein Phosphorylation as a Regulatory Modality: Implications for Mitochondrial Dysfunction in Heart Failure Cong. Heart Fail. 2011 Nov;17(6):269-82.

Angiotensin receptors and aging

badgef1000Abadir P, Foster DB, Crow M, Cooke C, Jain A, Smith B, Fedarko N, O’Rourke B, Walston JThe Identification and Characterization of a Mitochondrial Angiotensin System Proc. Natl. Acad. Sci. U. S. A 2011 Sep 6;108(36):14849-54. Epub 2011 Aug 18.Cutting Edge Science Pick. Appears in: Inagami T. Mitochondrial Angiotensin receptors and aging Circ Res. 2011 Dec 9;109(12):1323-4.Faculty of 1000-Recommended: Brown N:  2011 f1000.com/13340037#eval14707164

Cardiac resynchronization therapy and reverse molecular remodeling: importance of mitochondrial redox signaling

Wang SB, Foster DB, Rucker J, O’Rourke B, Kass DA and Van Eyk JE. Redox Regulation of Mitochondrial ATP synthase: Implications for Cardiac Resynchronization Therapy Circ. Res. 2011 Sep 16;109(7):750-7. Epub 2011 Aug 4.Featured Article (Editor’s Pick). Editorial appears in: Zweier JL, Chen CA, Talukder MA. Cardiac resynchronization therapy and reverse molecular remodeling: importance of mitochondrial redox signaling. Circ. Res. 2011 Sep 16;109(7):716-9.

Top Advances in Functional Genomics and Translational Biology for 2011

Cammarato A, Ahrens CH, Alayari NN, Qeli E, Rucker J, Zmasek C, Reedy MC, Gucek M, Cole RN, Van Eyk JE, Bodmer R, O’Rourke B, Bernstein SI, Foster DB A Mighty Small Heart: The Cardiac Proteome of Adult Drosophila melanogaster PLoS ONE. 2011 6(4): e18497. doi:10.1371/journal.pone.0018497. Top Advance:Barth AS, Ferguson JF and Musunuru K,Top Advances in Functional Genomics and Translational Biology for 2011 Circ. Cardiovasc. Genet. 2012, 5, 143-145.

Constitutive HIF-1α expression blunts the beneficial effects of cardiosphere-derived cell therapy in the heart via paracrine mechanisms

Bonios M, Chang CY, Terrovitis J, Pinheiro A, Afzal JM, Barth A,  Santaularia M, Foster DB, Engels J , Wahl R, Semenza G, Raman V, Abraham TP, Abraham MR. Constitutive HIF-1α expression blunts the beneficial effects of cardiosphere-derived cell therapy in the heart via paracrine mechanisms J. Cardiovasc. Transl. Res. 2011 Jun;4(3):363-72. Epub 2011 May 3.

Effect of Troponin I Ser23/24 Phosphorylation on Ca2+-Sensitivity in Human Myocardium Depends on Endogenous Phosphorylation Background

Kooij V, Saes M, Jaquet K, Zaremba R, Foster DB, Murphy AM, dos Remedios C, van der Velden J, Stienen GJM Effect of Troponin I Ser23/24 Phosphorylation on Ca2+-Sensitivity in Human Myocardium Depends on Endogenous Phosphorylation Background J. Mol. Cell. Cardiol. 2010 May;48(5):954-63.

The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments

Galinska A, Hatch V, Craig R, Murphy AM, Van Eyk JE, Wang C-LA, Lehman W, Foster DB The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments Circ. Res. 2010 Mar 5;106(4):705-11. Epub 2009 Dec 24.

Redox signaling and protein phosphorylation in mitochondria: progress and prospects

Foster DB, Van Eyk JE, Marbán E, O’Rourke B. Redox signaling and protein phosphorylation in mitochondria: progress and prospects J Bioenerg. Biomembr. 2009 Apr;41(2):159-68.

Miltenberger blood group antigen type III (Mi.III) enhances the expression of band 3

Hsu K, Chi N, Gucek M, Van Eyk JE, Cole RN, Lin M, Foster DB Miltenberger blood group antigen type III (Mi.III) enhances the expression of band 3 Blood. 2009 Aug 27;114(9):1919-28.

What can mitochondrial proteomics tell us about cardioprotection afforded by preconditioning?

Foster DB, O’Rourke B, Van Eyk JE,What can mitochondrial proteomics tell us about cardioprotection afforded by preconditioning? Expert Rev. Proteomics. 2008 Oct;5(5):633-6.