Brian and Lauren hit the Basic Cardiovascular Sciences 2018 Scientific Sessions in San Antonio, July 31-Aug2, last week. Brian presented his invited seminar entitled Altered Retinostasis in Heart Failure in the Tuesday session on Transcriptional Regulation and Epigenetics. Stunning talks by all the speakers, including Enzo Porello from Murdoch Children’s Research Institute, Tom Vondriska from […]
A few weeks ago we were thrilled to learn that the AHA has chosen to fund our work on altered retinoic acid homeostasis in heart failure progression with a Transformational Project Award. I wish to extend my thanks to the AHA, past and present members of the research team (Ni, Lauren & Kyriakos), as well […]
Dey S, DeMazumder D, Sidor A, Foster DB, O’Rourke B. Mitochondrial ROS Drive Sudden Cardiac Death and Chronic Proteome Remodeling in Heart Failure. Circ Res. 2018 Jul 20;123(3):356-371. doi: 10.1161/CIRCRESAHA.118.312708. Epub 2018 Jun 13.PMID: 29898892
Vakrou S, Fukunaga R, Foster DB, Sorensen L, Liu Y, Guan Y, Woldemichael K, Pineda-Reyes R, Liu T, Tardiff JC, Leinwand LA, Tocchetti CG, Abraham TP, O’Rourke B, Aon MA, Abraham MR. Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models. JCI Insight. 2018; 3(6). PMID: 29563334 PMCID: PMC5926940
Afzal J, Chan A, Karakas MF, Woldemichael K, Vakrou S, Guan Y, Rathmell J, Wahl R, Pomper M, Foster DB, Aon MA, Tsui B, O’Rourke B, Abraham MR. Cardiosphere-Derived Cells Demonstrate Metabolic Flexibility That Is Influenced by Adhesion Status. JACC. Basic to translational science. 2017; 2(5):543-560. NIHMSID: NIHMS939086 PMID: 29520378 PMCID: PMC5839118
Yikes, it’s been a while since the last update. As we begin 2017, this is a good time to reflect on the year that was. A source of pride in 2016 was the publication of the book Manual of Cardiovascular Proteomics, which I co-edited with Dr. Giulio Agnetti Assistant Professor of Medicine and Director of […]
In September 2016 we published the big one. I am referring to our paper: Integrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death. J Proteome Res. 2016 Sep 2;15(9):3009-28. doi: 10.1021/acs.jproteome.6b00149. PMID: 27399916 in which we examined the transcriptome, proteome and metabolome of heart failure progression in a modified […]
O’Rourke B, Liu T, and Foster DB Seeing the Forest for the Trees. Circ Res. 2016 Nov 11;119(11):1170-1172. PMID: 28051783
Foster DB, Liu T, Kammers K, O’Meally R, Yang N, Papanicolaou KN, Talbot CC Jr, Cole RN, O’Rourke B. Integrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death. J Proteome Res. 2016 Sep 2;15(9):3009-28. doi: 10.1021/acs.jproteome.6b00149. PMID: 27399916
Burks TN, Marx R, Powell L, Rucker J, Bedja D, Heacock E, Smith BJ, Foster DB, Kass D, O’Rourke B, Walston JD, Abadir PM. Combined effects of aging and inflammation on renin-angiotensin system mediate mitochondrial dysfunction and phenotypic changes in cardiomyopathies. Oncotarget. 2015;6(14):11979-93. Epub 2015/05/29. PubMed PMID: 26019138.
