Viswanathan MC, Blice-Baum AC, Schmidt W, Foster DB, Cammarato A. Pseudo-acetylation of K326 and K328 of actin disrupts Drosophila melanogaster indirect flight muscle structure and performance. Front Physiol. 2015;6:116. Epub 2015/05/15. doi: 10.3389/fphys.2015.00116. PubMed PMID: 25972811; PMCID: PMC4412121.
Ramirez-Correa GA, Frazier AH, Zhu G, Zhang P, Rappold T, Kooij V, Bedja D, Snyder GA, Lugo-Fagundo NS, Hariharan R, Li Y, Shen X, Gao WD, Cingolani OH, Takimoto E, Foster DB, Murphy AM. Cardiac troponin I Pro82Ser variant induces diastolic dysfunction, blunts beta-adrenergic response, and impairs myofilament cooperativity. J Appl Physiol (1985). 2015;118(2):212-23. Epub […]
Wijnker PJ, Li Y, Zhang P, Foster DB, dos Remedios C, Van Eyk JE, Stienen GJ, Murphy AM, van der Velden J. A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis. J Mol Cell Cardiol. 2015;82:93-103. Epub 2015/03/17. doi: 10.1016/j.yjmcc.2015.03.006. PubMed PMID: 25771144; […]
Papanicolaou KN, O’Rourke B, Foster DB. Metabolism leaves its mark on the powerhouse: recent progress in post-translational modifications of lysine in mitochondria. Front Physiol. 2014;5:301. Epub 2014/09/18. doi: 10.3389/fphys.2014.00301. PubMed PMID: 25228883; PMCID: PMC4151196.
Wijnker PJ, Sequeira V, Witjas-Paalberends ER, Foster DB, dos Remedios CG, Murphy AM, Stienen GJ, van der Velden J. Phosphorylation of protein kinase C sites Ser42/44 decreases Ca(2+)-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human cardiomyocytes. Arch Biochem Biophys. 2014;554:11-21. Epub 2014/05/13. doi: 10.1016/j.abb.2014.04.017. PubMed PMID: 24814372; PMCID: PMC4121669.
Fitzgerald R, De Santiago B, Lee DY, Yang G, Kim JY, Foster DB, Chan-Li Y, Horton MR, Panettieri, Jr. RA, Wang R, and An SS. H2S relaxes isolated human airway smooth muscle cells via the sarcolemmal KATP channel. Biochem Biophys Res Commun. 2014 Mar 28;446(1):393-8. doi: 10.1016/j.bbrc.2014.02.129. Epub 2014 Mar 12
Wijnker PJM, Sequeira V, Foster DB, Li Y, dos Remedios CG, Murphy AM, Stienen GJM, and van der Velden J. Length-dependent activation is modulated by cardiac troponin I bisphosphorylation at Ser23 and Ser24 but not by Thr143 phosphorylation. Am. J. Physiol. 2014 Feb 28. [Epub ahead of print]
Our most recent paper detailing the sites of lysine acetylation in the heart is now published
Foster DB*, Liu T, Rucker J, O’Meally B2, Hitt L, Cole RN, and O’RourkeB. The Cardiac Acetyl-Lysine Proteome PLoS One. 2013 Jul 2;8(7):e67513. Print 2013.*corresponding author
Sequeira V, Wijnker PJM, Nijenkamp LAM, Najafi A, Witjas-Paalberends R, Regan JA, Boontje, N, ten Cate FJ, Carrier L, Sadayappan S, van Slegtenhorst MA, Zaremba R, Foster DB, Murphy AM, Poggesi C, dos Remedios C, Stienen GJM, Michels M, van der Velden J. Perturbed length-dependent activation in human hypertrophic cardiomyopathy with sarcomere mutations in myosin […]
